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Unger T Sionov RV, Moallem E, Yee CL, Howley PM, Oren M et al (1999) Mutations in ser-ines 15 and 20 of human p53 impair its apoptotic activity. There is noethical basis for forcing fluids or nutrition upon a patient.
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Fundamental methodological considerations incontrolled clinical trials. Closed-angle glaucomashould be considered in the differential diagnosis of anypatient with new-onset headache developing after age50, especially with an acute red eye and reduced vision,but also with short-duration headaches (4 hours or less)that do not meet criteria for a defined headache syndrome(Shindler et al., 2005; Lanska, 2006). Thus, in both stud-ies, the no observed adverse effect level (NOAEL) was at orabove the highest dose level tested (100? MHD for acute,25? MHD for repeat dose, allometrically scaled). In patients with peripros-thetic knee infection, resection arthroplasty is generally followed by arthrodesis afterhealing of infection .
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